A synthetic anticoagulant: a polysulfuric acid ester of polyanhydromannuronic acid (paritol); experience with its use in man.
نویسندگان
چکیده
The effects of the use of Paritol administered intravenously to 35 individuals are herein reported. This synthetic anticoagulant produces a prolongation of the clotting time similar to that produced by heparin but of longer duration, if appropriate dosage is used. As with heparin, at therapeutic clotting time levels, the prothrombin time is slightly prolonged. Certain untoward effects have been noted and are described. Further studies with Paritol appear justified in order to evaluate its usefulnes3 as a rapidly acting anticoagulant.
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عنوان ژورنال:
- Circulation
دوره 2 5 شماره
صفحات -
تاریخ انتشار 1950